Β-pirazol-1-il alanina Índice Biosíntesis Síntesis Actividad biológica Referencias Menú de navegaciónNúmero CAS

Aminoácidos


cucurbitáceasácido 2,4-diaminobutíricopirazolidinapirazolserinaadición de Michael














 

L-β-Pirazol-1-ilalanina

L-β-Pyrazol-1-ylalanine.png
Nombre IUPAC

Ácido 2-amino-3-(1-pirazolil)propanoico
General
Fórmula molecular
C6H9N3O2
Identificadores
Número CAS
2734-48-7[1]​
Propiedades físicas
Masa molar
155.156 g/mol
Punto de descomposición
243 ℃ (516 K)
Valores en el SI y en condiciones estándar
(25 ℃ y 1 atm), salvo que se indique lo contrario.
[editar datos en Wikidata]

La L-β-Pirazol-1-ilalanina es una aminoácido no proteínico aislado de las semillas de la sandía (Citrullus vulgaris) y otras plantas cucurbitáceas. [α]20D = -73 (c, 3.4 en agua).[2]​




Índice





  • 1 Biosíntesis


  • 2 Síntesis


  • 3 Actividad biológica


  • 4 Referencias




Biosíntesis


La L-β-Pirazol-1-ilalanina es biosintetizada a partir del 1,3-diaminopropano (producto de descarboxilación del ácido 2,4-diaminobutírico). Esta amina forma el anillo de pirazolidina por heterociclización oxidativa de los extremos de nitrógeno. Seguido de esto, el compuesto sufre de oxidación para formar el anillo de pirazol, el cual se conjuga con una molécula de acetilserina[3]​


BIOSINTESIS DE B-PIRAZOL-1-IL-ALANINA.png


Síntesis


Ferreira y colaboradores establecieron una síntesis de β-Pirazol-1-ilalanina por adición de Michael del pirazol sobre el 2-[bis(ter-butoxicarbonil)amino]prop-2-enoato de metilo.[4]​


Síntesis de β-Pirazol-1-ilalanina.png


Actividad biológica


La β-(pirazol-1-il)-alanina presenta actividad hipoglicémica[5]​



Referencias



  1. ↑ Número CAS


  2. ↑ Dunnill, P.M. et al., Phytochemistry, 1965, 4, 933


  3. ↑ Frisch, D.M. et al., Phytochemistry, 1967, 6, 921


  4. ↑ Ferreira PMT, Maia HLS, Monteiro LS, Tetrahedron Lett., 1998;39:9575.


  5. ↑ Dunnill PM, Fowde L, Phytochemistry, 1965;4:935







-

Popular posts from this blog

Are there any comparative studies done between Ashtavakra Gita and Buddhim?How is it wrong to believe that a self exists, or that it doesn't?Can you criticise or improve Ven. Bodhi's description of MahayanaWas the doctrine of 'Anatta', accepted as doctrine by modern Buddhism, actually taught by the Buddha?Relationship between Buddhism, Hinduism and Yoga?Comparison of Nirvana, Tao and Brahman/AtmaIs there a distinction between “ego identity” and “craving/hating”?Are there many differences between Taoism and Buddhism?Loss of “faith” in buddhismSimilarity between creation in Abrahamic religions and beginning of life in Earth mentioned Agganna Sutta?Are there studies about the difference between meditating in the morning versus in the evening?Can one follow Hinduism and Buddhism at the same time?Are there any prohibitions on participating in other religion's practices?Psychology of 'flow'

Image
Why "be dealt cards" rather than "be dealing cards"? Have I saved too much for retirement so far? The plural of 'stomach" How do I rename a LINUX host without needing to reboot for the rename to take effect? What defines a dissertation? Why are on-board computers allowed to change controls without notifying the pilots? Bash method for viewing beginning and end of file Student evaluations of teaching assistants Opposite of a diet Go Pregnant or Go Home Valid Badminton Score? What's the purpose of "true" in bash "if sudo true; then" What is the intuitive meaning of having a linear relationship between the logs of two variables? The baby cries all morning Is there a good way to store credentials outside of a password manager? Can I use my Chinese passport to enter China after I acquired another citizenship? Why Were Madagascar and New Zealand Discovered So Late? What are the ramifications of creating a ...
Read more

Is compression “encryption” under FCC regs?Signing of messages transmitted over ham radioWhy do Amateur Radio organizations in the United States oppose the relaxation of encryption prohibitions?How far from earth do FCC regulations apply?How can I know whether a radio is FCC approved?FCC tracking of unlicensed FRS/GMRS transmissionsWhy does the FCC put restrictions on symbol rates?legal - Do FCC regulations only apply in U.S.A?What are FCC/Industry Canada certification requirements for amateur radio related products?How to get professional or official clarification of FCC Part 97 rules for specific complicated situations?Is there any point to keep the CSCE after the FCC registers the upgrade?Do FCC regulations limit digital data rate?

Image
What wound would be of little consequence to a biped but terrible for a quadruped? Are there historical instances of the capital of a colonising country being temporarily or permanently shifted to one of its colonies? Makefile strange variable substitution When a wind turbine does not produce enough electricity how does the power company compensate for the loss? Recommendation letter by significant other if you worked with them professionally? What do you call someone who likes to pick fights? Why does Captain Marvel assume the people on this planet know this? Why doesn't this Google Translate ad use the word "Translation" instead of "Translate"? Examples of a statistic that is not independent of sample's distribution? 'The literal of type int is out of range' con número enteros pequeños (2 dígitos) How does NOW work? What Happens when Passenger Refuses to Fly Boeing 737 Max? Is it possible to avoid unpacking when merging Asso...
Read more

How to reinstall a packageRestoring the script commandBroken package ubuntuone-control-panel-qtPackage Manager Error: setting up language-selector-commonInstalltion failed a .deb PackageNew software can't be installed, because there is a problem with the software currently installed. Do you want to repair this problem now?Package Operation Failed - Help neededHow to Remove varicad2013-en (A Virus or PIA)mysql-server-5.5 ErrorHow can I reinstall oracle-java-installer?dpkg: error processing package sendmail-basedpkg error processing package

Image
How can I, as DM, avoid the Conga Line of Death occurring when implementing some form of flanking rule? Animation: customize bounce interpolation What is the smallest number n> 5 so that 5 ^ n ends with "3125"? Does Doodling or Improvising on the Piano Have Any Benefits? Check if object is null and return null How to make a list of partial sums using forEach Alignment of six matrices Limit max CPU usage SQL SERVER with WSRM Why didn’t Eve recognize the little cockroach as a living organism? Review your own paper in Mathematics Difference between shutdown options Storage of electrolytic capacitors - how long? Can I run 125kHz RF circuit on a breadboard? I'm just a whisper. Who am I? Does the Crossbow Expert feat's extra crossbow attack work with the reaction attack from a Hunter ranger's Giant Killer feature? Why the "ls" command is showing the permissions of files in a FAT32 partition? What is this high flying aircraft ...
Read more