Β-pirazol-1-il alanina Índice Biosíntesis Síntesis Actividad biológica Referencias Menú de navegaciónNúmero CAS

Aminoácidos


cucurbitáceasácido 2,4-diaminobutíricopirazolidinapirazolserinaadición de Michael














 

L-β-Pirazol-1-ilalanina

L-β-Pyrazol-1-ylalanine.png
Nombre IUPAC

Ácido 2-amino-3-(1-pirazolil)propanoico
General
Fórmula molecular
C6H9N3O2
Identificadores
Número CAS
2734-48-7[1]​
Propiedades físicas
Masa molar
155.156 g/mol
Punto de descomposición
243 ℃ (516 K)
Valores en el SI y en condiciones estándar
(25 ℃ y 1 atm), salvo que se indique lo contrario.
[editar datos en Wikidata]

La L-β-Pirazol-1-ilalanina es una aminoácido no proteínico aislado de las semillas de la sandía (Citrullus vulgaris) y otras plantas cucurbitáceas. [α]20D = -73 (c, 3.4 en agua).[2]​




Índice





  • 1 Biosíntesis


  • 2 Síntesis


  • 3 Actividad biológica


  • 4 Referencias




Biosíntesis


La L-β-Pirazol-1-ilalanina es biosintetizada a partir del 1,3-diaminopropano (producto de descarboxilación del ácido 2,4-diaminobutírico). Esta amina forma el anillo de pirazolidina por heterociclización oxidativa de los extremos de nitrógeno. Seguido de esto, el compuesto sufre de oxidación para formar el anillo de pirazol, el cual se conjuga con una molécula de acetilserina[3]​


BIOSINTESIS DE B-PIRAZOL-1-IL-ALANINA.png


Síntesis


Ferreira y colaboradores establecieron una síntesis de β-Pirazol-1-ilalanina por adición de Michael del pirazol sobre el 2-[bis(ter-butoxicarbonil)amino]prop-2-enoato de metilo.[4]​


Síntesis de β-Pirazol-1-ilalanina.png


Actividad biológica


La β-(pirazol-1-il)-alanina presenta actividad hipoglicémica[5]​



Referencias



  1. ↑ Número CAS


  2. ↑ Dunnill, P.M. et al., Phytochemistry, 1965, 4, 933


  3. ↑ Frisch, D.M. et al., Phytochemistry, 1967, 6, 921


  4. ↑ Ferreira PMT, Maia HLS, Monteiro LS, Tetrahedron Lett., 1998;39:9575.


  5. ↑ Dunnill PM, Fowde L, Phytochemistry, 1965;4:935







-

Popular posts from this blog

Virtualbox - Configuration error: Querying “UUID” failed (VERR_CFGM_VALUE_NOT_FOUND)“VERR_SUPLIB_WORLD_WRITABLE” error when trying to installing OS in virtualboxVirtual Box Kernel errorFailed to open a seesion for the virtual machineFailed to open a session for the virtual machineUbuntu 14.04 LTS Virtualbox errorcan't use VM VirtualBoxusing virtualboxI can't run Linux-64 Bit on VirtualBoxUnable to insert the virtual optical disk (VBoxguestaddition) in virtual machine for ubuntu server in win 10VirtuaBox in Ubuntu 18.04 Issues with Win10.ISO Installation

Image
Fear of getting stuck on one programming language / technology that is not used in my country Do the primes contain an infinite almost arithmetic progression? Biological Blimps: Propulsion Are Captain Marvel's powers affected by Thanos' actions in Infinity War Why does AES have exactly 10 rounds for a 128-bit key, 12 for 192 bits and 14 for a 256-bit key size? Can a College of Swords bard use a Blade Flourish option on an opportunity attack provoked by their own Dissonant Whispers spell? Can disgust be a key component of horror? Can I say "fingers" when referring to toes? What is Cash Advance APR? Why Shazam when there is already Superman? What does "Scientists rise up against statistical significance" mean? (Comment in Nature) What does chmod -u do? What should you do when eye contact makes your subordinate uncomfortable? Issue while creating Apex class using API How much character growth crosses the line into breaking the charac...
Read more

How to disable autoformat in LibreOffice 6 Calc?Updating LibreOffice Calc 3.3.4How to run Libreoffice calcLibreOffice Calc - Disable roundingLibreoffice calc date format problemSimple query in LibreOffice Calclibreoffice calc -copy paste not workingExpand LibreOffice calc filter boxLibreOffice Calc Macro doesn't insert new sheetLibreoffice Calc Today Function Date Format?LibreOffice Calc - Delete empty rows

Image
What if you are holding an Iron Flask with a demon inside and walk into Antimagic Field? What are the balance implications behind making invisible things auto-hide? Calculating total slots What exact color does ozone gas have? Multiplicative persistence Does the UK parliament need to pass secondary legislation to accept the Article 50 extension How to hide some fields of struct in C? How do I delete all blank lines in a buffer? How can mimic phobia be cured? Mimic lecturing on blackboard, facing audience Terse Method to Swap Lowest for Highest? Why does the Sun have different day lengths, but not the gas giants? Strong empirical falsification of quantum mechanics based on vacuum energy density Why is the "ls" command showing permissions of files in a FAT32 partition? Quoting Keynes in a lecture How do apertures which seem too large to physically fit work? What is Cash Advance APR? Fear of getting stuck on one programming language / technology...
Read more

When should I use the pronoun “ri”?What is the meaning of “korekta” and when to use it?How do I know when to use the preposition “je”?When to use “olda” instead of “maljuna”?When should I use “tio” and “tiu”?When should I use “tiam, kiam” instead of just “kiam”?Should I ever use the pronoun “ci”?What words for different levels of education should I use?When to use “ĝin” and “tion”When should I use “tion, kion” or just “kion”?Why is there no plural “kio,” like “kioj?”

Image
If I can solve Sudoku, can I solve the Travelling Salesman Problem (TSP)? If so, how? Welcoming 2019 Pi day: How to draw the letter π? What is "focus distance lower/upper" and how is it different from depth of field? A diagram about partial derivatives of f(x,y) Examples of transfinite towers Why does overlay work only on the first tcolorbox? As a new Ubuntu desktop 18.04 LTS user, do I need to use ufw for a firewall or is iptables sufficient? Adventure Game (text based) in C++ Can I use USB data pins as power source Instead of a Universal Basic Income program, why not implement a "Universal Basic Needs" program? Is there a place to find the pricing for things not mentioned in the PHB? (non-magical) Fastest way to pop N items from a large dict combinatorics floor summation What is the Japanese sound word for the clinking of money? Why did it take so long to abandon sail after steamships were demonstrated? Python if-else code style for r...
Read more